Over the past few years, my wife has become a staunch antivaccinationist. (We
I agree with Professor Smith. The only thing I would add may be obvious and may be something you've already tried. It sometimes helps to have third parties intervene to provide all the facts and arguments you would use to try to persuade your wife to change her mind. Here, your knowledge of who might influence her is useful. Would she trust your family's pediatrician or react harshly against him/her as a member of the 'vaccine conspiracy'? Her parents or yours? Mutual friends? While an 'intervention' would be extreme, making friends and family aware of a serious issue that affects the health of your children (and others) and enlisting their help might make it easier for your wife to back down without feeling pressured to do so solely by you. But should these methods fail, then Prof. Smith's suggestion seems appropriate.